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Peritonitis - secundair (perforatie)

Advices

≥ 18 years
Priority Medication Remarks
Medication:

cefuroxim iv 1500mg 3dd

+

Metronidazol iv 500mg 3dd

+

tobramycine iv 5mg/kg 1dd

Remarks:

aminoglycoside totdat kweek bekend is

Medication:

ciprofloxacine iv 400mg 3dd

+

Metronidazol iv 500mg 3dd

Remarks:

Indien cefalosporine overgevoelig

Medication:

cotrimoxazol (trimethoprim +sulfamethoxazol) po 960mg 2dd

+

Metronidazol po 500mg 3dd

Remarks:

orale optie

Medication:

ciprofloxacine po 500mg 2dd

+

Metronidazol po 500mg 3dd

Remarks:

orale optie

General comments

Duur afhankelijk van kliniek. Maximaal 5 dagen behandelen indien goede source control. 

Sources

  1. Pubmed.gov publication # 25992746

    Trial of short-course antimicrobial therapy for intraabdominal infection. Sawyer RG, Claridge JA, Nathens AB, et al. N Engl J Med. 2015 May 21;372(21):1996-2005.

  2. WI Tobramycine bij volwassenen
Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

  • cefuroxim
  • Metronidazol
  • tobramycine
  • ciprofloxacine
  • cotrimoxazol (trimethoprim +sulfamethoxazol)
External antimicrobial resources
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Metadata

Swab vid: G-498601.2
Updated: 04/03/2023 - 11:04
Status: Published