Home Therapy Bones and joints
Home Therapy Bones and joints

Spondylodiscitis

Advices

≥ 18 years
Priority Medication Remarks
Medication:

flucloxacilline iv 1000mg 6dd

+

tobramycine iv 5mg/kg 1dd 3 to 5 days
Remarks:

Onbekende verwekker
Medication:

meropenem iv 1000mg dd 3

Remarks:

Onbekende verwekker

General comments

Start voor aanvang van antibiotische therapie met punctie.

Totale behandelduur minimaal 6 weken, switch naar oraal indien goede respons. 

Zie ook richtlijn: https://kwaliteitsportaal.itnet.local/iDocument/Viewers/Frameworks/ViewDocument.aspx?DocumentID=9a630708-8ea5-4303-8753-81ee2ce2b86a&NavigationHistoryID=7914543&PortalID=103&Query=spondylodiscitis

Sources

  1. Pubmed.gov publication # 25468170

    Bernard L, Dinh A, Ghout I, et al.; Duration of Treatment for Spondylodiscitis (DTS) study group. Antibiotic treatment for 6 weeks versus 12 weeks in patients with pyogenic vertebral osteomyelitis: an open-label, non-inferiority, randomised, controlled trial. Lancet. 2015;385:875-82.

  2. WI Tobramycine bij volwassenen
Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

  • flucloxacilline
  • tobramycine
  • meropenem
External antimicrobial resources
Menu position
Metadata

Swab vid: G-498520.2
Updated: 04/03/2023 - 10:55
Status: Published